Peptide receptors Angiotensin-IIAT1 (h) AT2 (h) Bombesinbb3 (h) B2 (h) Calcitonin gene-related peptideCGRP (h) ChemokineCCR1 (h) CholecystokininCCKA (h)

Παρουσίαση με θέμα: "Peptide receptors Angiotensin-IIAT1 (h) AT2 (h) Bombesinbb3 (h) B2 (h) Calcitonin gene-related peptideCGRP (h) ChemokineCCR1 (h) CholecystokininCCKA (h)"— Μεταγράφημα παρουσίασης:

1 Peptide receptors Angiotensin-IIAT1 (h) AT2 (h) Bombesinbb3 (h) B2 (h) Calcitonin gene-related peptideCGRP (h) ChemokineCCR1 (h) CholecystokininCCKA (h) CCKB (h) Complement 5aC5a (h) EndothelinETA (h) ETB (h) GalaninGAL1 (h) GlucagonGlucagon (h) Growth hormone secretagogueGhrelin (h) Melanin-concentrating hormoneMCH1 (h) MC1 (m) MC3 (h) MC4 (h) MotilinMotilin (h) NeurokininNK1 (h) NK2 (h) Neuropeptide YY1 (h) NeurotensinNT1 (h) Opioid and opioid-likedelta 2 (h) kappa (h) mu (h) ORL1 (h) Somatostatinsst4 (h) sst5 (h) Thyroid hormoneTH (r) Urotensin-IIUT1 (h) Vasoactive intestinal peptideVIP1 (h) PACAP (h) VasopressinV1a (h) V1b (h) V2 (h) Ion channels Ca2+ channels K+ channels Na+ channel Ca2+ channel (L, DHP site) Ca2+ channel (L, diltiazem site) Ca2+ channel (L, verapamil site) Ca2+ channel (N) Ryanodine (RY3) K+ATP channel (r) K+V channel (r) SK+Ca channel (r) Na+ channel (site 2) Amine transporter Choline Dopamine GABA Norepinephrine Seretonin NE transporter (h) DA transporter (h) GABA transporter Choline transporter (h) 5-HT transporter (h) Non-peptide receptors Nuclear receptors Glucocorticoid Estrogen alpha Androgen Adenosine Adrenergic Cannabinoid Dopamine GABA Glutamate Glycine Histamine Imidazole Leukotriene Melatonin Muscarinic Nicotinic Purinergic Serotonin Sigma GR (h) Eralpha (h) AR (h) A1 (h) A2A (h) A2B (h) A3 (h) alpha 1A (h) alpha 2A (h) alpha 2B (h) alpha 2C (h) beta 1 (h) beta 2 (h) beta 3 (h) CB1 (h) CB2 (h) D1 (h) D2S (h) D3 (h) D4.4 (h) GABAA (r) GABAB(1b) (h) BZD (central) (r) Cl- channel (r) AMPA (r) Kainate (r) NMDA (r) PCP (r) Glycine (strychnine-insensitive) (r) Glycine (strychnine-sensitive) (r) H1 (h) H2 (h) H3 (h) I1(b) LTD4 (h) ML1 (c) ML2 (MT3) (ham) M1 (h) M2 (h) M3 (h) M4 (h) M5 (h) N (neuronal) (α-BGTX-insensitive) (r) N (muscle-type) (h) P2X (r) 5-HT1A (h) 5-HT1B (h) 5-HT1D (r) 5-HT2A (h) 5-HT2B (h) (agonist site) 5-HT2C (h) 5-HT3 (h) 5-HT4e (h) 5-HT6 (h) 5-HT7 (h) sigma (non-selective) (r) CaMK2α (h) ERK2 (h) p56Fyn kinase (h) p55Lyn kinase (h) ZAP70 kinase (h) Abl kinase (h) Protein kinase C (r) Protein kinase B-α (h) CDK1 Phosphatase 1B (h) Phosphatase C (r) Elastase (h) Tryptase (h) ACE (h) BACE-1 (h) TACE (h) HIV-1 protease (h) ACE (h) Neutral endopeptidase (h) MMP-1 (h) MMP-2 (h) MMP-3 (h) MMP-7 (h) MMP-9 (h) Cathepsin X (h) Cathepsin L (h) Cathepsin H (h) Cathepsin G (h) Cathepsin E (h) Cathepsin D (h) Cathepsin B (h) m-Calpain (r) m -Calpain (h) Granzyme B (h) Phosphodiesterases PDE2 (h) PDE3 (h) PDE4 (h) PDE5 (h) PDE6 (b) Arachidonic acid/ COX1 (h) prostaglandin metabolism COX2 (h) PGE2 secretion (h) Monoamine and neurotransmitter MAO-A (h) synthesis and metabolism MAO-B (h) GABA transaminase (r) Acetylcholinesterase (h) COMT (Catechol- O-methyl transferase) (p) Histamine N-Methyltransferase (h) Tyrosine hydroxylase (r) Nitric oxide synthesis Cerebellar constitutive NOS (r) Endothelial constitutive NOS (h) Second messenger systems Guanylyl cyclase (b) ATPases ATPase (Na+/K+) (d) Lipid synthesis HMG-CoA reductase (ham) Miscellaneous enzymes Carbonic anhydrase II (h) Xanthine oxidase Kinases Phosphatases Phospholipases Proteases Enzymes Supplementary Table 3, Chauvier et al..2011